Abstract
Objective: to present the clinical and epidemiological characteristics of patients referred for MRI brain due to seizures, along with their corresponding MRI findings.
Study design: It is a descriptive observational study
Place and duration of study: The study was conducted at Radiology department of POF Hospital Wah Cantt.
Material and Methods: Retrospective data from consecutive patients with fits who underwent MRI brain from August 2020 to September 2023 were analyzed (n=536). Patients' data were obtained from the local database and MRI forms. All MRI reports were assessed by Radiologists. Results were analyzed using SPSS-25.
Results: 50.6% (n=271) males and 49.4% (n=265) females were included in the study. 0- 15yrs age group consisted of 40.7% (n=218) patients. Positive MRI findings were found in 67.4% of the patients. Findings in 17.9% of the patients were ischemic changes, in 11.9% of the patients were infections, 8.6% of the patients had neoplasm, out of which gliomas were most common followed by meningiomas, 8.4% patients had hemorrhage and 6% of the patients had congenital diseases. Regarding co-morbidities, 9% patients (n=48) had infections versus 88.6% patients (n=475) with no comorbidity. Majority of the patients 49.4% (n=265) had no other symptom along with fits, while 21.6% (n=116) of the patients had fever along with fits.
Conclusion: MRI is a vital tool for determining the underlying etiology of seizures and directing therapeutic choices. The results of MRI show differences between different age groups.
Keywords: Fits, Seizures, Epilepsy, MRI
References
Pallewatte AS, Alahakoon S, Senanayake G, Bulathsinghela BC. An analysis of MRI findings in patient reffered with fits. Sri Lanka Journal of Radiology. 2015;1: 6-12.
Bernasconi A, Cendes F, Theodore WH, Gill RS, Koepp MJ, Hogan RE, Jackson GD, Federico P, Labate A, Vaudano AE, Blümcke I. Recommendations for the use of structural magnetic resonance imaging in the care of patients with epilepsy: a consensus report from the International League Against Epilepsy Neuroimaging Task Force. Epilepsia. 2019 Jun;60(6):1054-68.
Beghi E. The epidemiology of epilepsy. Neuroepidemiology. 2020 Dec 18;54(2):185-91.
Goldstein LH, Robinson EJ, Reuber M, Chalder T, Callaghan H, Eastwood C, Landau S, McCrone P, Medford N, Mellers JD, Moore M. Characteristics of 698 patients with dissociative seizures: a UK multicenter study. Epilepsia. 2019 Nov;60(11):2182-93.
Sen A, Jette N, Husain M, Sander JW. Epilepsy in older people. The Lancet. 2020 Feb 29;395(10225):735-48.
Herrera H, Luthen R. Pre‐school Child with Seizures. Cases in Pediatric Acute Care: Strengthening Clinical Decision Making. 2020 Apr 15:81-4.
Kalnin AJ, Fastenau PS, deGrauw TJ, Musick BS, Perkins SM, Johnson CS, et al. MR imaging findings in children with first recognized seizure. Paediatric Neurology. 2008;39(6): 404-414.
Durkin MS, Davidson LL, Hasan ZM, Hasan Z, Hauser WA, Khan N, et al. Paediatric and Perinatal Epidimiology. 1992;6(2): 166-180.
Kondapavuluri SK. A study of evaluation of seizure disorder with magnetic resonance imaging in a teritiary care hospital.Journal of Cadiovascular Disease Research.2023
Yoganathan K, Malek N, Torzillo E, Paranathala M, Greene J. Neurological update: structural and functional imaging in epilepsy surgery. Journal of Neurology. 2023 May;270(5):2798-808.
King MA, Newton MR, Jackson GD, Fitt GJ, Mitchell LA, Silvapulle MJ, et al. Epileptology of the first-seizure presentation: a clinical, electroencephalographic, and magnetic resonance imaging study of 300 consecutive patients. Lancet. 1998;352(9133): 1007-1011.
Gamage R. Management of epilepsy. Clinical practice guide lines Sri Lanka. 2013;4: 15-16.
Arora V, Nijjar I, Mahajan DS, Sandhu PS, Singh JP, Chopra R. MRI in seizure disorder - a pictorial essay. Indian J Radiol Imaging. 2005;15(3): 331-340.
Shih-Hui L. Epidemiology and etiology of seizures and epilepsy in the elderly in Asia. Neurology. 2004;9 (Supplement 1): 31-32
Durkin MS, Davidson LL, Hasan ZM, Hasan Z, Hauser WA, Khan N, Paul TJ, Shrout PE, Thorburn MJ, Zaman S. Estimates of the prevalence of childhood seizure disorders in communities where professional resources are scarce: results from Bangladesh, Jamaica and Pakistan. Paediatric and perinatal epidemiology. 1992 Apr;6(2):166-80.
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