Abstract
Objective: To examine and evaluate the diagnostic accuracy of ultrasound and magnetic resonance cholangiopancreatography (MRCP) in establishing a diagnosis of choledocholithiasis, and to compare the findings with the gold standard, ERCP.
Study design: It is a prospective study design
Place and duration of study: This four month study was carried out in Jahangir SON-X Diagnostic Center, Rawalpindi.
Material and Methods: 200 patients suffering from symptoms with suspicion of choledocholithiasis were referred for ERCP. All the patients went through ultrasound and MRCP examinations and then the diagnosis for choledocholithiasis through these modalities was compared with the results of ERCP.
Results: Keeping ERCP as gold standard in choledocholithiasis diagnosis, Ultrasound showed a diagnostic accuracy, sensitivity, and specificity of 49%, 43% and 100%, respectively. MRCP depicted diagnostic accuracy, sensitivity, and specificity of 99%, 99% and 94%, respectively. One false-positive and one false-negative findings have been identified by the MRCP results.
Conclusion: The diagnosis of choledocholithiasis is accurately done by MRCP, showing higher sensitivity and diagnostic accuracy than Ultrasound. Ultrasound shows higher specificity than MRCP.
Keywords: Endoscopic Retrograde Cholangiopancreatography (ERCP), Intra-Operative Cholangiography (IOC), Magnetic Resonance Cholangiopancreatography (MRCP), Endoscopic Ultrasound (EUS), Percutaneous Transhepatic Cholangiography (PTC).
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