Effectiveness Of Normal Saline Versus Tetrachlorodecaoxide Dressing In The Management Of Diabetic Foot Wounds

Abstract

Introduction: Pure solutions are used to produce an electrically treated aqueous solution high in reactive oxygen species
(ROS). It is a potent anti-microbial. TCDO has been shown to be bactericidal in vitro. Wound healing is made possible by the
mitogenic activities of TCDO on fibroblasts and new blood vessels. The primary goal of this study to Compare the effectiveness
of Normal Saline Dressings versus Tetrachlorodecaoxide Dressings in the management of Diabetic Foot Wounds. The study
was conducted at Department of Gen eral Surgery, Postgraduate Medical Institute/Shaikh Zayed Hospital, Lahore. Aim is to
compare the effectiveness of normal saline versus tetrachlorodecaoxide dressing in the management of diabetic foot wounds.

Methods: A sample size of 40 (20 in each group) in group A, dressing was done with normal saline and in group B, dressing
was done with tetrachlorodecaoxide solution. Statistical analyses were performed using IBM SPSS version 20. The mean
difference was calculated using an independent t -test, and catego rical variables were stratified using a chi square test or a
Fisher exact test as appropriate.

Results: Normal saline significantly shortened the healing duration and wound area after 8 weeks when added to a routine
therapy for DFU. A comprehensive strategy is nece ssary to treat DFU effectively. To assist limit the number of patients who
may eventually have to have their legs amputated due to DFU -related complications, it may be possible that normal salt water
can be used as an alternate treatment option.

Conclusion: In conclusion, normal saline significantly shortened the healing duration and wound area after 8 weeks when
added to a conventional therapy for DFU. A comprehensive strategy is necessary to treat DFU effectively. To assist limit the
number of patients who may eventually have to have their legs amputated due to DFU -related complications, it may be
possible that normal salt water can be used as an alternate treatment option.

Keywords: Diabetes, Normal saline, Tetrachlorodecaoxide, Diabetic foot, Foot ulcers, Super-oxidized solution