Neurological Manifestations In Typhoid Fever During The First Week Of Illness: A Case Report

Abstract

Typhoid fever, a classical example of enteric fever, is a
potentially fatal, multi-systemic illness caused
primarily by Salmonella enterica serovar typhi.1
Typhoid is a major public health problem in many
developing countries of the world. 80% of the cases of
Typhoid are reported from Bangladesh, Pakistan,
China, India, Indonesia, Nepal and Vietnam2
. Its
classical presentation includes fever, malaise, diffuse
abdominal pain, and constipation. However, it can
also present with symptoms of confused mental state,
acute psychosis,, meningo-encephalitis, myelitis,
cerebellitis, parkinsonism and generalized anxiety
disorders.3,4
Neurological complications following typhoid fever
usually occur during the third week of illness. These
complications are rarely observed during the first
week of illness. Here we report a case of a 17 year old
boy who developed sensory aphasia and dystonic
jerks during first week of typhoid fever.