Abstract
Background: Cholecystectomy is one of the most
frequently performed surgical procedures across the
globe and is considered as a treatment of choice for
majority cases of acute cholecystitis.
Empyema/gangrene is one of the most frequent and
important complication of acute cholecystitis. World
over, the association between gender and the
complications associated with acute cholecystitis is
poorly documented. The purpose of the study was to
find out the frequency of empyema/gangrene in
acute cholecystitis and to determine its relation with
gender.
Methods: This cross-sectional descriptive study,
was conducted at histopathology laboratory,
Department of Pathology, Holy Family Hospital,
Rawalpindi, by reviewing past medical record of
(2016) of 76 patients(38 males and 38 females) of
acute cholecystitis selected on the basis of nonprobability consecutive sampling. Data was
analysed using SPSS 23.
Results: Out of 76 patients, 25(32.9%) patients of
acute cholecystitis developed empyema/gangrene.
Out of 38 males, 17(45%) developed
empyema/gangrene as a complication whereas out of
38 females only 8(21%) developed
empyema/gangrene. A statistically significant
portion of male patients developed
empyema/gangrene, [p=0.028].
Conclusion: Male gender has a statistically
significant relationship of developing
empyema/gangrene in acute cholecystitis. This may
help in prioritizing the patients for surgery.
Keywords: Bladder, Male gender.